(Rac)-Minzasolmin
Product Sizes
5 mg
£ POA
HY-125287-5MG
25 mg
£ POA
HY-125287-25MG
10 mg
£ POA
HY-125287-10MG
10mM/1mL
£ POA
HY-125287-10MM
About this Product
- SKU:
- HY-125287
- Additional Names:
- (Rac)-UCB0599; NPT200-11
- CAS Number:
- 1802518-63-3
- Extra Details:
- (Rac)-Minzasolmin ((Rac)-UCB0599; NPT200-11) is a blood-brain barrier penetrated alpha-synuclein (ASYN) misfolding inhibitor. (Rac)-Minzasolmin acts on the early stage of ASYN aggregation process; by replacing the membrane-bound oligomers ASYN; allowing them to revert to the monomeric form; while preventing pathological aggregation. (Rac)-Minzasolmin effectively improves the ASYN deposition in the retina and the neuro-pathological indicators in two α-synuclein transgenic mouse models. (Rac)-Minzasolmin can be used for the studies of Parkinson's disease (PD) and dementia with Lewy bodies (DLB)[1].
- Molecular Weight:
- 425.59
- Purity:
- 99.87
- References:
- [1]Price DL, et al. The small molecule alpha-synuclein misfolding inhibitor, NPT200-11, produces multiple benefits in an animal model of Parkinson's disease. Sci Rep. 2018 Nov 1;8(1):16165.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Neuronal Signaling
