PF-06380101
Product Sizes
10 mg
£ POA
HY-12522-10MG
25 mg
£ POA
HY-12522-25MG
100 mg
£ POA
HY-12522-100MG
5 mg
£ POA
HY-12522-5MG
50 mg
£ POA
HY-12522-50MG
10mM/1mL
£ POA
HY-12522-10MM
About this Product
- SKU:
- HY-12522
- Additional Names:
- Aur0101; Auristatin-0101
- Application:
- Antibody Microarray
- CAS Number:
- 1436391-86-4
- Extra Details:
- PF-06380101 (Aur0101); an auristatin microtubule inhibitor; is a cytotoxic Dolastatin 10 analogue. PF-06380101 (Aur0101) shows excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs.
- Molecular Weight:
- 743.01
- Purity:
- 99.95
- References:
- [1]Maderna A, et al. Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications. J Med Chem. 2014 Dec 26;57(24):10527-43.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Conjugated Protein
- Pathway:
- Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton
