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Proteins and Peptides

(Rac)-ZLc-002

Product Sizes
100 mg
£ POA
HY-124996-100MG
50 mg
£ POA
HY-124996-50MG
25 mg
£ POA
HY-124996-25MG
10 mg
£ POA
HY-124996-10MG
5 mg
£ POA
HY-124996-5MG
10mM/1mL
£ POA
HY-124996-10MM
About this Product
SKU:
HY-124996
Extra Details:
(Rac)-ZLc-002; an inhibitor of nNOS interaction with nitric oxide synthase 1 adaptor protein (NOS1AP); suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with Paclitaxel (HY-B0015) to reduce tumor cell viability[1][2].
Molecular Weight:
231.25
Purity:
98.96
References:
[1]Lee WH, Carey LM, Li LL, et al. ZLc002, a putative small-molecule inhibitor of nNOS interaction with NOS1AP, suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability. Mol Pain. 2018;14:1744806918801224.|[2]Zhu LJ, Shi HJ, Chang L, et al. nNOS-CAPON blockers produce anxiolytic effects by promoting synaptogenesis in chronic stress-induced animal models of anxiety. Br J Pharmacol. 2020;177(16):3674-3690.
Research Area:
Cancer; Inflammation/Immunology; Neurological Disease
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Immunology/Inflammation
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