(3S;5S)-Atorvastatin (sodium salt)
Product Sizes
Get quote
£ POA
HY-123632-1EACH
About this Product
- SKU:
- HY-123632
- Application:
- Immunoprecipitation
- CAS Number:
- 1428118-38-0
- Extra Details:
- (3S;5S)-Atorvastatin sodium salt is a pregnane X receptor (PXR) activator and the inactive enantiomer of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor with lipid-lowering capabilities[1].
- Molecular Weight:
- 580.62
- References:
- [1]Kocarek TA, et al. Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes. Drug Metab Dispos. 2002 Dec;30(12):1400-5.|[2]Korhonova M, et al. Optical Isomers of Atorvastatin, Rosuvastatin and Fluvastatin Enantiospecifically Activate Pregnane X Receptor PXR and Induce CYP2A6, CYP2B6 and CYP3A4 in Human Hepatocytes. PLoS One. 2015 Sep 14;10(9):e0137720.|[3]Shcherbakova EG, et al. High-Throughput Assay for Enantiomeric Excess Determination in 1,2- and 1,3-Diols and Direct Asymmetric Reaction Screening. Chemistry. 2017 Jul 26;23(42):10222-10229.
- Research Area:
- Others
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
