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Proteins and Peptides

KRCA-0008

Product Sizes
10 mg
£ POA
HY-12331-10MG
25 mg
£ POA
HY-12331-25MG
5 mg
£ POA
HY-12331-5MG
100 mg
£ POA
HY-12331-100MG
50 mg
£ POA
HY-12331-50MG
10mM/1mL
£ POA
HY-12331-10MM
About this Product
SKU:
HY-12331
CAS Number:
1472795-20-2
Extra Details:
KRCA-0008 is a selective ALK/Ack1 inhibitor with IC50s of 12 and 4 nM for ALK and Ack1; respectively. KRCA-0008 can be used for the research of cancer[1][2].
Molecular Weight:
609.12
Purity:
96.72
References:
[1]Park CH, et al. Novel bis-ortho-alkoxy-para-piperazinesubstituted-2,4-dianilinopyrimidines (KRCA-0008) as potent and selective ALK inhibitors for anticancer treatment. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6192-6.|[2]Hwang J, et al. KRCA-0008 suppresses ALK-positive anaplastic large-cell lymphoma growth. Invest New Drugs. 2020 Oct;38(5):1282-1291.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Apoptosis;Protein Tyrosine Kinase/RTK
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