GSA-10
Product Sizes
5 mg
£ POA
HY-12317-5MG
100 mg
£ POA
HY-12317-100MG
25 mg
£ POA
HY-12317-25MG
50 mg
£ POA
HY-12317-50MG
1 mg
£ POA
HY-12317-1MG
10 mg
£ POA
HY-12317-10MG
About this Product
- SKU:
- HY-12317
- Application:
- Antibody Microarray
- CAS Number:
- 300833-95-8
- Extra Details:
- GSA-10 is a potent smooth (Smo) receptor agonist. GSA-10 is a potent osteogenic molecule. GSA-10 can mediate Hedgehog (Hh) signaling. GSA-10 can be used in regenerative medicine for cancer disease and in the study of fat development[1][2][3].
- Molecular Weight:
- 450.53
- Purity:
- 98.0
- References:
- [1]Gorojankina T, et al. Discovery, molecular and pharmacological characterization of GSA-10, a novel small-molecule positive modulator of Smoothened. Mol Pharmacol. 2013 May;83(5):1020-9. |[2]Manetti F, et al. Design, synthesis and biological characterization of a new class of osteogenic (1H)-quinolone derivatives. Eur J Med Chem. 2016 Oct 4;121:747-757. |[3]Fleury A, et al. Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathway. Sci Rep. 2016 Mar 24;6:23479. doi: 10.1038/srep23479. PMID: 27010359; PMCID: PMC4806302.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C; 3 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Stem Cell/Wnt
