Arg-Gly-Asp-Ser
Product Sizes
5 mg
£ POA
HY-12290-5MG
10 mg
£ POA
HY-12290-10MG
50 mg
£ POA
HY-12290-50MG
100 mg
£ POA
HY-12290-100MG
10mM/1mL
£ POA
HY-12290-10MM
About this Product
- SKU:
- HY-12290
- Additional Names:
- RGDS peptide; Fibronectin tetrapeptide
- CAS Number:
- 91037-65-9
- Extra Details:
- Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8; pro-caspase-9 and pro-caspase-3; while it does not bind pro-caspase-1.
- Molecular Weight:
- 433.42
- Purity:
- 99.09
- References:
- [1]Grigoriou V, et al. Apoptosis and survival of osteoblast-like cells are regulated by surface attachment. J Biol Chem. 2005 Jan 21;280(3):1733-9.|[2]Moon C, et al. Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir Res. 2009 Mar 9;10:18.|[3]Yin X, et al. Synthetic RGDS peptide attenuated lipopolysaccharide/D-galactosamine-induced fulminant hepatic failure in mice. J Gastroenterol Hepatol. 2014 Jun;29(6):1308-15.|[4]Aguzzi MS, et al. Intracellular targets of RGDS peptide in melanoma cells. Mol Cancer. 2010 Apr 22;9:84.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Pathway:
- Cytoskeleton
