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Proteins and Peptides

(E/Z)-E64FC26

Product Sizes
5 mg
£ POA
HY-122895A-5MG
50 mg
£ POA
HY-122895A-50MG
10 mg
£ POA
HY-122895A-10MG
100 mg
£ POA
HY-122895A-100MG
10mM/1mL
£ POA
HY-122895A-10MM
25 mg
£ POA
HY-122895A-25MG
About this Product
SKU:
HY-122895A
Application:
Antibody Microarray
CAS Number:
2285446-67-3
Extra Details:
(E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family; with IC50s of 1.9; 20.9; 25.9; 16.3; and 25.4 μM against PDIA1; PDIA3; PDIA4; TXNDC5; and PDIA6. E64FC26 shows anti-myeloma activity[1][2].
Molecular Weight:
340.38
Purity:
99.80
References:
[1]Nathan G. Dolloff, et al. Indene derivatives and uses thereof. US20190062298A1.|[2]Robinson RM, et al. Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma. Leukemia. 2019 Apr;33(4):1011-1022.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Apoptosis;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
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