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Proteins and Peptides

MM-206

Product Sizes
5 mg
£ POA
HY-121725-5MG
10 mg
£ POA
HY-121725-10MG
About this Product
SKU:
HY-121725
CAS Number:
1809581-87-0
Extra Details:
MM-206; a STAT3 activity inhibitor; potently inhibits the STAT3 SH2 domain-phosphopeptide interaction with IC50 of 1.2 μM. MM-206 demonstrates dose-dependent induction of apoptosis in acute myeloid leukemia (AML) cell lines[1].
Molecular Weight:
497.46
Purity:
99.9
References:
[1]A Novel STAT3 Inhibitor Has Potent Activity in Preclinical Models of Acute Myeloid Leukemia That Incorporate the Stromal Environment. Blood.2015 Dec 3.126 (23): 569.
Research Area:
Cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C; 3 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
JAK/STAT Signaling;Stem Cell/Wnt
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