(5Z;2E)-CU-3
Product Sizes
10 mg
£ POA
HY-121638A-10MG
25 mg
£ POA
HY-121638A-25MG
50 mg
£ POA
HY-121638A-50MG
100 mg
£ POA
HY-121638A-100MG
5 mg
£ POA
HY-121638A-5MG
10mM/1mL
£ POA
HY-121638A-10MM
About this Product
- SKU:
- HY-121638A
- Application:
- Antibody Microarray
- CAS Number:
- 1815598-71-0
- Extra Details:
- (5Z;2E)-CU-3 is an isomer of CU-3 (HY-121638). CU-3 is a DGKα inhibitor with an IC50 of 0.6 μM. CU-3 competitively reduces DGKα’s affinity for ATP via binding to the enzyme’s catalytic region. CU-3 induces apoptosis in cancer cells. CU-3 promotes T-cell activation and enhances IL-2 production. CU-3 can be used for the research of hepatocellular carcinoma and cervical cancer[1].
- Molecular Weight:
- 392.47
- Purity:
- 98.04
- References:
- [1]Liu K, et al. A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response. J Lipid Res. 2016 Mar;57(3):368-79.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis;Metabolic Enzyme/Protease
