(S)-Bromoenol lactone
Product Sizes
1 mg (3.15 mM * 1 mL in Methyl acetate)
£ POA
HY-120986-1MG
About this Product
- SKU:
- HY-120986
- Additional Names:
- (S)-BEL; (S;E)-Bromoenol lactone
- CAS Number:
- 478288-94-7
- Extra Details:
- (S)-Bromoenol lactone ((S)-BEL) is an irreversible; chiral; mechanism-based inhibitor of calcium-independent phospholipase A2β (iPLA2β) that inhibits the vasopressin-induced release of arachidonate from cultured rat aortic smooth muscle (A10) cells with an IC50 of 2 µM[1].
- Molecular Weight:
- 317.18
- Purity:
- 99.1
- References:
- [1]Jenkins CM, et al. Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discrimination of mammalian iPLA2s. J Biol Chem. 2002 Sep 6;277(36):32807-14.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Solution; -20[o]C; 2 years
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
