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Proteins and Peptides

(rel)-AM-6226

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HY-120493-1EACH
About this Product
SKU:
HY-120493
CAS Number:
1142222-28-3
Extra Details:
(rel)-AM-6226 is the relative stereoisomer of AM-6226 (HY-120493A). AM-6226 is a potent; orally active full agonist of G protein-coupled receptor 40 (GPR40) with an EC50 value of 0.12 μM. AM-6226 activates GPR40 receptors on pancreatic β-cells and enteroendocrine L-cells; promotes insulin secretion in a glucose-dependent manner; and increases the release of incretin hormones (GLP-1; GIP); thus avoiding the risk of hypoglycemia. AM-6226 can be used in the research of metabolic diseases such as diabetes[1].
Molecular Weight:
522.62
Research Area:
Metabolic Disease
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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