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Proteins and Peptides

Samelisant

Product Sizes
100 mg
£ POA
HY-120124-100MG
5 mg
£ POA
HY-120124-5MG
10 mg
£ POA
HY-120124-10MG
25 mg
£ POA
HY-120124-25MG
50 mg
£ POA
HY-120124-50MG
10mM/1mL
£ POA
HY-120124-10MM
About this Product
SKU:
HY-120124
Additional Names:
SUVN-G3031
CAS Number:
1394808-20-8
Extra Details:
Samelisant (SUVN-G3031) is a potent and selective histamine H3 receptor (H3R) inverse agonist with good brain penetration and oral bioavailability. Samelisant has a similar binding affinity towards human (hH3R; Ki=8.7 nM) and rat (rH3R;Ki=9.8 nM) H3R indicating no inter-species differences. Samelisant can be used for the research of sleep-related disorders[1].
Molecular Weight:
446.41
Purity:
98.04
References:
[1]Ramakrishna Nirogi, et al. Samelisant (SUVN-G3031), a potent, selective and orally active histamine H3 receptor inverse agonist for the potential treatment of narcolepsy: pharmacological and neurochemical characterisation. Psychopharmacology (Berl). 2021 Jun;238(6):1495-1511.
Research Area:
Neurological Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C; 3 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
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