(S)-MDL-101146
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HY-120039A-1EACH
About this Product
- SKU:
- HY-120039A
- CAS Number:
- 163660-59-1
- Extra Details:
- (S)-MDL-101146 is the S-isomer of MDL-101146. MDL-101146 is an orally active; competitive and reversible inhibitor against human neutrophil elastase (HNE) with a Ki value of 25 nM. MDL-101146 inhibits HNE-induced hemorrhage in hamsters. MDL-101146 is promising for research of emphysema; rheumatoid arthritis; chronic bronchitis; cystic fibrosis; adult respiratory distress syndrome and glomerulonephritis[1].
- Molecular Weight:
- 632.62
- References:
- [1]Angelastro MR, et al. Inhibition of human neutrophil elastase with peptidyl electrophilic ketones. 2. Orally active PG-Val-Pro-Val pentafluoroethyl ketones. J Med Chem. 1994 Dec 23;37(26):4538-53.
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
