PF-06827443
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HY-120004-1EACH
About this Product
- SKU:
- HY-120004
- CAS Number:
- 2115022-67-6
- Extra Details:
- PF-06827443 is a potent; low-clearance; orally bioavailable; and CNS-penetrant M1-selective positive allosteric modulator (PAM) with minimal agonist activity. PF-06827443 induce cholinergic AEs and convulsion[1].
- Molecular Weight:
- 404.46
- References:
- [1]Jennifer E Davoren, et, al. Design and Synthesis of γ- and δ-Lactam M1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M1-Selective PAM with Weak Agonist Activity. J Med Chem. 2017, 60, 15.
- Research Area:
- Infection
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
