(Rac)-OSMI-1
Product Sizes
25 mg
£ POA
HY-119738A-25MG
10 mg
£ POA
HY-119738A-10MG
50 mg
£ POA
HY-119738A-50MG
5 mg
£ POA
HY-119738A-5MG
10mM/1mL
£ POA
HY-119738A-10MM
About this Product
- SKU:
- HY-119738A
- Application:
- Immunoprecipitation
- CAS Number:
- 2748153-92-4
- Extra Details:
- (Rac)-OSMI-1 is the racemate of OSMI-1. OSMI-1 is a cell-permeable O-GlcNAc transferase (OGT) inhibitor with an IC50 value of 2.7 μM. OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans[1][2].
- Molecular Weight:
- 563.64
- Purity:
- 96.51
- References:
- [1]Ortiz-Meoz RF, et al. A small molecule that inhibits OGT activity in cells. ACS Chem Biol. 2015 Jun 19;10(6):1392-7.|[2]Liu Y, et al. Discovery of a Low Toxicity O-GlcNAc Transferase (OGT) Inhibitor by Structure-based Virtual Screening of Natural Products. Sci Rep. 2017 Sep 26;7(1):12334.
- Research Area:
- Metabolic Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease;Neuronal Signaling
