(Rac)-Tavapadon
Product Sizes
50 mg
£ POA
HY-119486A-50MG
10 mg
£ POA
HY-119486A-10MG
100 mg
£ POA
HY-119486A-100MG
5 mg
£ POA
HY-119486A-5MG
10mM/1mL
£ POA
HY-119486A-10MM
25 mg
£ POA
HY-119486A-25MG
About this Product
- SKU:
- HY-119486A
- Additional Names:
- (Rac)-PF-06649751; (Rac)-CVL-751
- CAS Number:
- 1643462-64-9
- Extra Details:
- (Rac)-Tavapadon ((Rac)-PF-06649751) is a potent and selective noncatechol dopamine D1 receptor agonist. (Rac)-Tavapadon displays potent full agonism in the GS activation assay as well as partial agonism in the β-arrestin2 recruitment assay (GS-cAMP; EC50=0.8 nM; β-arrestin2; EC50=68 nM). (Rac)-Tavapadon has antiparkinsonian activity[1].
- Molecular Weight:
- 391.34
- Purity:
- 99.49
- References:
- [1]Michael L Martini, et al. Designing Functionally Selective Noncatechol Dopamine D 1 Receptor Agonists with Potent In Vivo Antiparkinsonian Activity. ACS Chem Neurosci. 2019 Sep 18;10(9):4160-4182.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein;Neuronal Signaling
