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Proteins and Peptides

ATM Inhibitor-10

Product Sizes
1 mg
£ POA
HY-118911-1MG
5 mg
£ POA
HY-118911-5MG
25 mg
£ POA
HY-118911-25MG
100 mg
£ POA
HY-118911-100MG
50 mg
£ POA
HY-118911-50MG
10 mg
£ POA
HY-118911-10MG
10mM/1mL
£ POA
HY-118911-10MM
About this Product
SKU:
HY-118911
CAS Number:
1941214-06-7
Extra Details:
ATM Inhibitor-10 (compound 74); a 3-quinoline carboxamide; is a highly selective and orally active ATM inhibitor (IC50: 0.6 nM). ATM Inhibitor-10 has anti-tumor activity in SW620 xenograft models. ATM Inhibitor-10 is synergistic with Top I inhibitors[1].
Molecular Weight:
434.47
Purity:
98.7
References:
[1]Degorce SL, et al. Discovery of Novel 3-Quinoline Carboxamides as Potent, Selective, and Orally Bioavailable Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase. J Med Chem. 2016 Jul 14;59(13):6281-92.
Research Area:
cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C; 3 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
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