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Proteins and Peptides

(E/Z)-BML264

Product Sizes
100 mg
£ POA
HY-118628-100MG
25 mg
£ POA
HY-118628-25MG
50 mg
£ POA
HY-118628-50MG
10mM/1mL
£ POA
HY-118628-10MM
About this Product
SKU:
HY-118628
Additional Names:
N-(p-Amylcinnamoyl) anthranilic acid; ACA
CAS Number:
110683-10-8
Extra Details:
(E/Z)-BML264 (N-(p-amylcinnamoyl) Anthranilic Acid) is a broad spectrum Phospholipase A2 (PLA2) inhibitor and TRP channel blocker[1][2]. (E/Z)-BML264 (N-(p-amylcinnamoyl) Anthranilic Acid) is also an effective reversible inhibitor of calcium-activated chloride channels; has potential to treat arrhythmia[3].
Molecular Weight:
337.41
Purity:
99.63
References:
[1]Kraft R, et al. Inhibition of TRPM2 cation channels by N-(p-amylcinnamoyl)anthranilic acid. Br J Pharmacol. 2006 Jun;148(3):264-73.|[2]Harteneck C, et al. N-(p-amylcinnamoyl)anthranilic acid (ACA): a phospholipase A(2) inhibitor and TRP channel blocker. Cardiovasc Drug Rev. 2007 Spring;25(1):61-75.|[3]Gwanyanya A, et al. Inhibition of the calcium-activated chloride current in cardiac ventricular myocytes by N-(p-amylcinnamoyl)anthranilic acid (ACA). Biochem Biophys Res Commun. 2010 Nov 19;402(3):531-6.
Research Area:
Cardiovascular Disease
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
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