(Rac)-CCT 250863
Product Sizes
1 mg
£ POA
HY-117884-1MG
About this Product
- SKU:
- HY-117884
- Application:
- Antibody Microarray
- CAS Number:
- 1364269-06-6
- Extra Details:
- (Rac)-CCT 250863 (compound rac-21) is a selective and reversible NEK 2 inhibitor with an IC50 of 0.073 µM. (Rac)-CCT 250863 shows good effects of inducing cell cycle arrest and also can antiproliferative in cells (Pomalidomide sensitive/resistant). (Rac)-CCT 250863 induces apoptosis when combines with Pomalidomide[1][2].
- Molecular Weight:
- 490.54
- Purity:
- 99.50
- References:
- [1]Ahsan A, et al. Methods for treating cancer with combination therapies. WO2021262962A1. |[2]Innocenti P, et al. Design of potent and selective hybrid inhibitors of the mitotic kinase Nek2: structure-activity relationship, structural biology, and cellular activity. J Med Chem. 2012 Apr 12;55(7):3228-41.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Apoptosis
