(E/Z)-Mirin
Product Sizes
100 mg
£ POA
HY-117693-100MG
10 mg
£ POA
HY-117693-10MG
50 mg
£ POA
HY-117693-50MG
5 mg
£ POA
HY-117693-5MG
10mM/1mL
£ POA
HY-117693-10MM
25 mg
£ POA
HY-117693-25MG
About this Product
- SKU:
- HY-117693
- CAS Number:
- 299953-00-7
- Extra Details:
- (E/Z)-Mirin is a mixture of (E)-Mirin and Mirin ((Z)-Mirin) (HY-19959) configurations. Among them; Mirin is an inhibitor of MRN (Mre11-Rad50-Nbs1). Mirin prevents MRN-dependent ATM activation without affecting ATM protein kinase activity[1][2].
- Molecular Weight:
- 220.25
- Purity:
- 99.22
- References:
- [1]Dupré A, et al. A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex. Nat Chem Biol. 2008;4(2):119-125.|[2]Ying S, et al. Mre11-dependent degradation of stalled DNA replication forks is prevented by BRCA2 and PARP1. Cancer Res. 2012;72(11):2814-2821.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; sealed storage; away from moisture and light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;PI3K/Akt/mTOR
