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Proteins and Peptides

BLT-1

Product Sizes
5 mg
£ POA
HY-116767-5MG
10 mg
£ POA
HY-116767-10MG
50 mg
£ POA
HY-116767-50MG
10mM/1mL
£ POA
HY-116767-10MM
25 mg
£ POA
HY-116767-25MG
100 mg
£ POA
HY-116767-100MG
250 mg
£ POA
HY-116767-250MG
About this Product
SKU:
HY-116767
Additional Names:
Block lipid transport-1
Application:
Immunoprecipitation
CAS Number:
321673-30-7
Extra Details:
BLT-1; a thiosemicarbazone copper chelator; is a selective scavenger receptor B; type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor[1][2][3][4].
Molecular Weight:
241.40
Purity:
99.93
References:
[1]Raldúa D, et al. BLT-1, a specific inhibitor of the HDL receptor SR-BI, induces a copper-dependent phenotype during zebrafish development. Toxicol Lett. 2007 Dec 10;175(1-3):1-7. Epub 2007 Aug 22.|[2]Nieland TJ, et al. Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity. Biochemistry. 2008 Jan 8;47(1):460-72.|[3]Nieland TJ, et al. Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptorSR-BI. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15422-7.|[4]Hirofumi Ohashi, et al. Reply to Padmanabhan and Dixit: Hepatitis C virus entry inhibitors for optimally boosting direct-acting antiviral-based treatments. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4527-E4529.
Research Area:
Metabolic Disease; Inflammation/Immunology
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Anti-infection
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