116-9e
Product Sizes
50 mg
£ POA
HY-116683-50MG
25 mg
£ POA
HY-116683-25MG
10 mg
£ POA
HY-116683-10MG
100 mg
£ POA
HY-116683-100MG
5 mg
£ POA
HY-116683-5MG
10mM/1mL
£ POA
HY-116683-10MM
About this Product
- SKU:
- HY-116683
- Additional Names:
- MAL2-11B
- CAS Number:
- 831217-43-7
- Extra Details:
- 116-9e (MAL2-11B) is a Hsp70 co-chaperone DNAJA1 inhibitor. 116-9e inhibits Simian Virus 40 (SV40) replication and DNA synthesis. 116-9e inhibits tumor antigen (TAg)’s endogenous ATPase activity and the TAg-mediated activation of Hsp70[1][2].
- Molecular Weight:
- 512.60
- Purity:
- 98.28
- References:
- [1]Christine M Wright, et al. Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen. Virus Res. 2009 Apr;141(1):71-80.|[2]Nitika, et al. Chemogenomic screening identifies the Hsp70 co-chaperone DNAJA1 as a hub for anticancer drug resistance. Sci Rep. 2020 Aug 14;10(1):13831.
- Research Area:
- Cancer; Infection
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
