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Proteins and Peptides

(6R)-ML753286

Product Sizes
1 mg
£ POA
HY-116494A-1MG
5 mg
£ POA
HY-116494A-5MG
10 mg
£ POA
HY-116494A-10MG
10mM/1mL
£ POA
HY-116494A-10MM
About this Product
SKU:
HY-116494A
Application:
Antibody Microarray
Extra Details:
(6R)-ML753286 is an isomer of ML753286 (HY-116494). ML753286 is an orally active and selective BCRP (Breast cancer resistance protein) inhibitor with an IC50 of 0.6 μM. ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions; and is stable in plasma cross species[1].
Molecular Weight:
355.43
Purity:
98.0
References:
[1]Liao M, et al. Preclinical absorption, distribution, metabolism, excretion and pharmacokinetics of a novelselective inhibitor of breast cancer resistance protein (BCRP). Xenobiotica. 2018 May;48(5):467-477.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Others
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