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Proteins and Peptides

(Rac)-Calpain Inhibitor XII

Product Sizes
5 mg
£ POA
HY-116171-5MG
About this Product
SKU:
HY-116171
Application:
Electron Microscopy
CAS Number:
181769-57-3
Extra Details:
(Rac)-Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I (μ-calpain; Ki=19 nM). (Rac)-Calpain Inhibitor XII has lower affinities for calpain II (m-calpain; Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac)-Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes; including neutrophil chemotaxis; neuronal signaling; and cardiac response to injury[1].
Molecular Weight:
482.57
Purity:
99.04
References:
[1]Z Li, et al. Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases. J Med Chem. 1996 Sep 27;39(20):4089-98.
Research Area:
Neurological Disease; Cardiovascular Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C (Powder; stored under nitrogen)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Metabolic Enzyme/Protease
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