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Proteins and Peptides

(E/Z)-BIO-acetoxime

Product Sizes
1 mg
£ POA
HY-114903-1MG
About this Product
SKU:
HY-114903
Additional Names:
GSK-​3 Inhibitor X
Application:
Immunoprecipitation
CAS Number:
740841-15-0
Extra Details:
(E/Z)-BIO-acetoxime (GSK-3 Inhibitor X) is a potent and selective GSK-3α/β inhibitor; with an IC50 of 10 nM. (E/Z)-BIO-acetoxime shows more than 200-flod selectivity over CDK5/p25; CDK2/cyclin A and CDK1/cyclin B (IC50=2.4; 4.3; 63 μM)[1].
Molecular Weight:
398.21
Purity:
99.9
References:
[1]Meijer L, et, al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol. 2003 Dec;10(12):1255-66.
Research Area:
Cancer; Metabolic Disease; Neurological Disease
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Cell Cycle/DNA Damage;PI3K/Akt/mTOR;Stem Cell/Wnt
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