11-Beta-hydroxyandrostenedione
Product Sizes
25 mg
£ POA
HY-114464-25MG
10 mg
£ POA
HY-114464-10MG
5 mg
£ POA
HY-114464-5MG
50 mg
£ POA
HY-114464-50MG
10mM/1mL
£ POA
HY-114464-10MM
About this Product
- SKU:
- HY-114464
- Additional Names:
- 4-Androsten-11β-ol-3;17-dione
- Application:
- Electron Microscopy
- CAS Number:
- 382-44-5
- Extra Details:
- 11-Beta-hydroxyandrostenedione (4-Androsten-11β-ol-3;17-dione) is a steroid mainly found in the the adrenal origin (11β-hydroxylase is present in adrenal tissue; but absent in ovarian tissue). 11-Beta-hydroxyandrostenedione is a 11β-hydroxysteroid dehydrogenase (11βHSD) isozymes inhibitor. As 4-androstenedione increases; measuring plasma 11-Beta-hydroxyandrostenedione can distinguish the adrenal or ovarian origin of hyperandrogenism[1][2].
- Molecular Weight:
- 302.41
- Purity:
- 99.97
- References:
- [1]Ibrahim F, et al. Plasma 11beta-hydroxy-4-androstene-3,17-dione: comparison of a time-resolved fluoroimmunoassay using a biotinylated tracer with a radioimmunoassay using a tritiated tracer. J Steroid Biochem Mol Biol. 2003 Apr;84(5):563-8.|[2]Rachelle Gent, et al. 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17αhydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol
- Research Area:
- Endocrinology
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
