Canine Thrombin
Product Sizes
100 μg
£ POA
HY-114164F-100UG
About this Product
- SKU:
- HY-114164F
- CAS Number:
- 9002-04-4
- Extra Details:
- Canine Thrombin is a Canine serine protease that plays a central role in blood coagulation. Canine Thrombin stimulates macrophages to polarize into a unique phenotype characterized by anti-inflammatory and pro-repair properties. Canine Thrombin activates PAR1; induces the production of MCP-1; MMP3 and VEGF in intervertebral discs; and causes degradation of the cartilage matrix and destruction of intervertebral disc structure. Canine Thrombin activity increases significantly in paraoxon-induced status epilepticus[1][2][3][4].
- References:
- [1]Golderman V, et al. Thrombin and the Protease-Activated Receptor-1 in Organophosphate-Induced Status Epilepticus. J Mol Neurosci. 2018 Dec 4.
- Research Area:
- Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
