Cyclic GMP (TBAOH)
Product Sizes
5 mg
£ POA
HY-113469B-5MG
25 mg
£ POA
HY-113469B-25MG
10 mg
£ POA
HY-113469B-10MG
About this Product
- SKU:
- HY-113469B
- Application:
- Antibody Microarray
- Extra Details:
- Cyclic GMP (cGMP) TBAOH; an important second messenger; is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP TBAOH occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs); cGMP-gated cation channels; and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512); a conjugate of Cyclic GMP and AMP; can induce IRF3 phosphorylation and nuclear translocation; enhancing antiviral immune responses[1][2][3][4].
- Molecular Weight:
- 604.68
- Purity:
- 99.07
- References:
- [1]Wu J, et al. Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science. 2013 Feb 15;339(6121):826-30.|[2]Jenal U, et al. Cyclic di-GMP: second messenger extraordinaire. Nat Rev Microbiol. 2017 May;15(5):271-284.
- Research Area:
- Infection; Inflammation/Immunology; Cardiovascular Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; stored under nitrogen; away from moisture)
- Type:
- Molecular Biology Reagents: Nucleic Acids
- Pathway:
- Immunology/Inflammation;Metabolic Enzyme/Protease
