1-Methyladenine
Product Sizes
5 mg
£ POA
HY-113306-5MG
About this Product
- SKU:
- HY-113306
- CAS Number:
- 5142-22-3
- Extra Details:
- 1-Methyladenine is a gonad maturation-promoting regulator. 1-Methyladenine is produced in testes and ovarian follicle cells of starfish under the induction of gonad-stimulating substance (GSS). 1-Methyladenine promotes starfish oocyte maturation and spawning; and modifies bases that regulate DNA structure. 1-Methyladenine converts T?A base pairs in double-stranded DNA into non-disruptive T (anti)?m1A (syn) Hoogsteen conformation. If this conformational base is not repaired in a timely manner; it transforms into cytotoxic DNA damage and blocks the replication process[1][2].
- Molecular Weight:
- 149.15
- Purity:
- 99.99
- References:
- [1]Falnes PØ, et al. Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins. Nucleic Acids Res. 2004 Dec 1;32(21):6260-7. Print 2004.|[2]Yang H, et al. Effect of 1-methyladenine on double-helical DNA structures. FEBS Lett. 2008 May 14;582(11):1629-33.
- Research Area:
- Others
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 4[o]C (Powder; protect from light)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
