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Proteins and Peptides

Cysteinylglycine

Product Sizes
100 mg
£ POA
HY-113110-100MG
5 mg
£ POA
HY-113110-5MG
25 mg
£ POA
HY-113110-25MG
50 mg
£ POA
HY-113110-50MG
10 mg
£ POA
HY-113110-10MG
About this Product
SKU:
HY-113110
Additional Names:
L-Cysteinylglycine; Cys-Gly; H-Cys-Gly-OH
Application:
Electron Microscopy
CAS Number:
19246-18-5
Extra Details:
Cysteinylglycine (L-Cysteinylglycine; Cys-Gly) is a dipeptide formed by the peptide bond linkage between cysteine (Cysteine) and glycine (Glycine). Cysteinylglycine is an important metabolic intermediate in the human body; mainly derived from the degradation of glutathione (GSH). Cysteinylglycine reduces ferric iron to ferrous iron; drives the redox cycle of iron; generates reactive oxygen species (ROS); stimulates oxidative reactions; induces lipid peroxidation of human plasma LDL lipoproteins; and causes oxidative damage to DNA bases. Cysteinylglycine can be used as a biomarker to evaluate ischemic heart disease; breast cancer and other conditions[1][2][3][4].
Molecular Weight:
178.21
Purity:
99.96
References:
[1]Houghton SC, et al. Plasma B-vitamin and one-carbon metabolites and risk of breast cancer before and after folicacid fortification in the United States. Int J Cancer. 2019 Apr 15;144(8):1929-1940.|[2]Steele M L, et al. Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells. Redox biology, 2013, 1(1): 441-445.|[3]Mansoor MA, et al. Determination of the in vivo redox status of cysteine, cysteinylglycine, homocysteine, and glutathione in human plasma. Anal Biochem. 1992 Feb 1;200(2):218-29.|[4]Lin J, et al. Plasma cysteinylglycine levels and breast cancer risk in women. Cancer Res. 2007 Dec 1;67(23):11123-7.
Research Area:
Cancer;Cardiovascular Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
-80[o]C; 2 years; -20[o]C; 1 year (Powder; sealed storage; away from moisture and light; under nitrogen)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Metabolic Enzyme/Protease
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