1-Methyladenosine
Product Sizes
50 mg
£ POA
HY-113081-50MG
100 mg
£ POA
HY-113081-100MG
10mM/1mL
£ POA
HY-113081-10MM
About this Product
- SKU:
- HY-113081
- CAS Number:
- 15763-06-1
- Extra Details:
- 1-Methyladenosine is an RNA modification that can serve as a tumor marker; with elevated levels in the body associated with cancer development. Following 1-methyladenosine methylation; upregulation of PPARδ expression regulates cholesterol metabolism and activates Hedgehog signaling pathway; driving liver tumorigenesis[1][2][3].
- Molecular Weight:
- 281.27
- Purity:
- 99.92
- References:
- [1]Hauenschild R, et al. The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent. Nucleic Acids Res. 2015 Nov 16;43(20):9950-64.|[2]Banys K, et al. Effect of Genistein Supplementation on the Progression of Neoplasms and the Level of the Modified Nucleosides in Rats With Mammary Cancer. In Vivo. 2021 Jul-Aug;35(4):2059-2072. |[3]Wang Y, et al. N 1-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism[J]. Nature communications, 2021, 12(1): 6314.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Stem Cell/Wnt;Vitamin D Related/Nuclear Receptor
