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Proteins and Peptides

(1S;2S;3R)-DT-061

Product Sizes
100 mg
£ POA
HY-112929B-100MG
5 mg
£ POA
HY-112929B-5MG
10 mg
£ POA
HY-112929B-10MG
50 mg
£ POA
HY-112929B-50MG
25 mg
£ POA
HY-112929B-25MG
10mM/1mL
£ POA
HY-112929B-10MM
About this Product
SKU:
HY-112929B
Application:
Antibody Microarray
CAS Number:
1809427-20-0
Extra Details:
(1S;2S;3R)-DT-061 is an enantiomer of DT-061 (HY-112929). DT-061 is an orally active activator of protein phosphatase 2A (PP2A). (1S;2S;3R)-DT-061 can be used as a negative control in the research of KRAS-mutant and MYC-driven lung cancer tumorigenesis[1].
Molecular Weight:
520.52
Purity:
99.77
References:
[1]Kauko O, et al. PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells. Sci Transl Med. 2018 Jul 18;10(450). pii: eaaq1093.
Research Area:
Cancer
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C; 3 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Metabolic Enzyme/Protease
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