(3S;4R)-ME-344
Product Sizes
10 mg
£ POA
HY-112749B-10MG
25 mg
£ POA
HY-112749B-25MG
50 mg
£ POA
HY-112749B-50MG
5 mg
£ POA
HY-112749B-5MG
10mM/1mL
£ POA
HY-112749B-10MM
About this Product
- SKU:
- HY-112749B
- CAS Number:
- 1374524-84-1
- Extra Details:
- (3S;4R)-ME-344 is the (3S;4R)-enantiomer of ME-344 (HY-112749). ME-344 is a mitochondrial Heme oxygenase 1 (HO-1) inhibitor. ME-344 specifically binds and alters HO-1 structure; and increases HO-1 translocation from the rough endoplasmic reticulum to mitochondria; but only in drug-sensitive cells (such as H460 and SHP-77 cells). ME-344 decreases mitochondrial ATP production and induces ROS; with subsequent disruption of redox homeostasis and mitochondrial function. ME-344 has significant antitumor activity; and can be used for cancers like breast cancer research[1].
- Molecular Weight:
- 348.39
- Purity:
- 98.04
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
