(S)-CR8
Product Sizes
1 mg
£ POA
HY-112371-1MG
5 mg
£ POA
HY-112371-5MG
About this Product
- SKU:
- HY-112371
- CAS Number:
- 1084893-56-0
- Extra Details:
- (S)-CR8 is the S-isomer of CR8. (S)-CR8 is a potent and selective CDK inhibitor with IC50s of 0.060; 0.080; 0.11; 0.12; and 0.15 μM for CDK2/cyclin E; CDK2/cyclin A; CDK9/cyclin T; CDK5/p25; and CDK1/cyclin B; respectively. (S)-CR8 reduces SH-SY5Y cells survival (IC50 0.40 μM)[1].
- Molecular Weight:
- 431.53
- Purity:
- 99.0
- References:
- [1]K Bettayeb, et al. CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases. Oncogene. 2008 Oct 2;27(44):5797-807.
- Research Area:
- Cancer
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C; 3 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Cell Cycle/DNA Damage
