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Proteins and Peptides

(E/Z)-ZL0420

Product Sizes
50 mg
£ POA
HY-112149A-50MG
100 mg
£ POA
HY-112149A-100MG
25 mg
£ POA
HY-112149A-25MG
10 mg
£ POA
HY-112149A-10MG
5 mg
£ POA
HY-112149A-5MG
About this Product
SKU:
HY-112149A
CAS Number:
2229039-45-4
Extra Details:
(E/Z)-ZL0420 is a racemic compound of (Z)-ZL0420 and (E)-ZL0420 isomers. (E)-ZL0420 is a potent and selective bromodomain-containing protein 4 (BRD4) inhibitor with IC50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2[1].
Molecular Weight:
296.32
References:
[1]Zhiqing Liu, et al. Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation. Eur J Med Chem. 2018 May 10;151:450-461.
Research Area:
Cancer; Inflammation/Immunology
Shipping Conditions:
Ambient
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Epigenetics
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