(Rac)-ACT-451840
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HY-111817A-1EACH
About this Product
- SKU:
- HY-111817A
- CAS Number:
- 1839508-99-4
- Extra Details:
- (Rac)-ACT-451840 is an isomer of ACT-451840 that exhibits significant antimalarial effects. (Rac)-ACT-451840 exhibits significant antimalarial activity against P. berghei-infected mice at a dose of 20 mg/kg (ED90=13 mg/kg); and has an inhibitory effect at a dose of 300 mg/kg. The ED90 of (Rac)-ACT-451840 in the P. falciparum humanized immunodeficient mouse model is 3.7 mg/kg. (Rac)-ACT-451840 is similar to artemisinin; with a rapid onset of action but requires repeated high doses.
- Molecular Weight:
- 750.97
- References:
- [1]Discovery and characterization of ACT‐451840: an antimalarial drug with a novel mechanism of action
- Research Area:
- infection
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
