(S)-LY-3381916
Product Sizes
5 mg
£ POA
HY-111540B-5MG
100 mg
£ POA
HY-111540B-100MG
10 mg
£ POA
HY-111540B-10MG
50 mg
£ POA
HY-111540B-50MG
25 mg
£ POA
HY-111540B-25MG
10mM/1mL
£ POA
HY-111540B-10MM
About this Product
- SKU:
- HY-111540B
- Additional Names:
- (S)-IDO1-IN-5
- Application:
- Antibody Microarray
- CAS Number:
- 2166616-76-6
- Extra Details:
- (S)-LY-3381916 ((S)-IDO1-IN-5; Example 1B) is an active S-isomer of LY-3381916. (S)-LY-3381916 binds to IDOL with an IC50 value less than 1.5 µΜ[1]. LY-3381916 is a potent; selective and brain penetrated inhibitor of Indoleamine 2;3-Dioxygenase 1 (IDO1) activity; binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[2].
- Molecular Weight:
- 396.45
- Purity:
- 99.06
- References:
- [1]Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).|[2]Jolie Anne Bastian, et al. 1-tetrahydropyranylcarbonyl-2,3-dihydro-1h-indole compounds for treating cancer. WO2017213919A1.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
