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Proteins and Peptides

(Rac)-LY-3381916

Product Sizes
100 mg
£ POA
HY-111540A-100MG
10 mg
£ POA
HY-111540A-10MG
25 mg
£ POA
HY-111540A-25MG
5 mg
£ POA
HY-111540A-5MG
50 mg
£ POA
HY-111540A-50MG
10mM/1mL
£ POA
HY-111540A-10MM
About this Product
SKU:
HY-111540A
Additional Names:
(Rac)-IDO1-IN-5
Application:
Antibody Microarray
CAS Number:
2166616-74-4
Extra Details:
(Rac)-LY-3381916 ((Rac)-IDO1-IN-5; Example 1) is a racemate of LY-3381916[1]. LY-3381916 is a potent; selective and brain penetrated inhibitor of Indoleamine 2;3-Dioxygenase 1 (IDO1) activity; binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1[2].
Molecular Weight:
396.45
Purity:
99.12
References:
[1]Frank C. Dorsey, et al. Abstract 5245: Identification and characterization of the IDO1 inhibitor LY3381916. Cancer Research. 2018, 78(13).|[2]Jolie Anne Bastian, et al. 1-tetrahydropyranylcarbonyl-2,3-dihydro-1h-indole compounds for treating cancer. WO2017213919A1.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Metabolic Enzyme/Protease
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