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Proteins and Peptides

(Rac)-Finerenone

Product Sizes
5 mg
£ POA
HY-111372A-5MG
1 mg
£ POA
HY-111372A-1MG
About this Product
SKU:
HY-111372A
Additional Names:
(Rac)-BAY 94-8862
CAS Number:
1050477-27-4
Extra Details:
(Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation; selective; and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR); androgen receptor (AR); and progesterone receptor (>500-fold)[1].
Molecular Weight:
378.42
Purity:
99.66
References:
[1]Bärfacker L, et al. Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseases. ChemMedChem. 2012;7(8):1385-1403.
Research Area:
Cardiovascular Disease
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
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