Pregnenolone monosulfate (sodium)
Product Sizes
25 mg
£ POA
HY-110189-25MG
50 mg
£ POA
HY-110189-50MG
10 mg
£ POA
HY-110189-10MG
100 mg
£ POA
HY-110189-100MG
10mM/1mL
£ POA
HY-110189-10MM
About this Product
- SKU:
- HY-110189
- Additional Names:
- 3β-Hydroxy-5-pregnen-20-one monosulfate (sodium)
- Application:
- Antibody Microarray
- CAS Number:
- 1852-38-6
- Extra Details:
- Pregnenolone monosulfate sodium (3β-Hydroxy-5-pregnen-20-one monosulfate sodium) is a powerful neurosteroid; the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate sodium acts as a signaling-specific inhibitor of cannabinoid CB1 receptor; inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate sodium can protect the brain from cannabis intoxication[1][2]. Pregnenolone monosulfate sodium is also a TRPM3 channel activator; and also can weakly activate TRPM1 channels[3].
- Molecular Weight:
- 418.52
- Purity:
- 99.96
- References:
- [1]Vallée M, et al. Pregnenolone can protect the brain from cannabis intoxication. Science. 2014 Jan 3;343(6166):94-8.|[2] Ducharme N, et al. Brain distribution and behavioral effects of progesterone and pregnenolone after intranasal or intravenous administration. Eur J Pharmacol. 2010 Sep 1;641(2-3):128-34.|[3]Alan Shiels. TRPM3_miR-204: a complex locus for eye development and disease. Hum Genomics. 2020 Feb 18;14(1):7.
- Research Area:
- Neurological Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Autophagy;GPCR/G Protein;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
