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Proteins and Peptides

SP-141

Product Sizes
10 mg
£ POA
HY-110182-10MG
50 mg
£ POA
HY-110182-50MG
100 mg
£ POA
HY-110182-100MG
25 mg
£ POA
HY-110182-25MG
5 mg
£ POA
HY-110182-5MG
10mM/1mL
£ POA
HY-110182-10MM
About this Product
SKU:
HY-110182
Application:
Antibody Microarray
CAS Number:
1253491-42-7
Extra Details:
SP-141 is a specific inhibitor of MDM2. SP-141 promotes MDM2 auto-ubiquitination and degradation. SP-141 might be used for the research of pancreatic cancer and breast cancer cells[1].
Molecular Weight:
324.38
Purity:
98.93
References:
[1]Wei Wang , et al. Identification of a New Class of MDM2 Inhibitor That Inhibits Growth of Orthotopic Pancreatic Tumors in Mice. Gastroenterology. 2014 Oct;147(4):893-902.e2.|[2]Wei Wang, et al. The Pyrido[b]indole MDM2 Inhibitor SP-141 Exerts Potent Therapeutic Effects in Breast Cancer Models. Nat Commun. 2014 Oct 1;5:5086.
Research Area:
Cancer
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C; 3 years; 4[o]C; 2 years (Powder)
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
Pathway:
Apoptosis
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