(E/Z)-3PO
Product Sizes
5 mg
£ POA
HY-110169-5MG
25 mg
£ POA
HY-110169-25MG
50 mg
£ POA
HY-110169-50MG
1 mg
£ POA
HY-110169-1MG
10 mg
£ POA
HY-110169-10MG
100 mg
£ POA
HY-110169-100MG
About this Product
- SKU:
- HY-110169
- Application:
- Antibody Microarray
- CAS Number:
- 13309-08-5
- Extra Details:
- (E/Z)-3PO is a potent PFKFB3 inhibitor. (E/Z)-3PO can inhibit the glycolysis process; reduce the extracellular acidification rate; and inhibit the capillary tube formation; migration of endothelial cells; and the formation of aortic sprouts; thereby suppressing angiogenesis. (E/Z)-3PO is promising for research of diseases such as cancer; acute lung injury; pulmonary fibrosis; and atherosclerosis[1].
- Molecular Weight:
- 210.24
- Purity:
- 99.86
- References:
- [1]Emini Veseli B, et al. Small molecule 3PO inhibits glycolysis but does not bind to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3). FEBS Lett. 2020 Sep;594(18):3067-3075.
- Research Area:
- Cancer; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
