(E)-KN-93 (phosphate)
Product Sizes
10 mg
£ POA
HY-110140-10MG
5 mg
£ POA
HY-110140-5MG
25 mg
£ POA
HY-110140-25MG
10mM/1mL
£ POA
HY-110140-10MM
About this Product
- SKU:
- HY-110140
- CAS Number:
- 1188890-41-6
- Extra Details:
- (E)-KN-93 phosphate is an inhibitor for Ca2+/calmodulin-dependent protein kinase II (CaMK II) with IC50 of 9 μM and 3 μM; for CaMKIIδ monomer and CaMKIIδ dodecamer. (E)-KN-93 phosphate binds competitively with Ca2+/CaM; and disrupts their interaction with CaMK II; and thus inhibits the CaMK II activation[1].
- Molecular Weight:
- 599.03
- Purity:
- 99.85
- References:
- [1]Wong MH, et al., The KN-93 Molecule Inhibits Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity by Binding to Ca2+/CaM. J Mol Biol. 2019 Mar 29;431(7):1440-1459.
- Research Area:
- Neurological Disease; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- RT; stored under nitrogen
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Neuronal Signaling
