(Z)-Guggulsterone (Standard)
Product Sizes
5 mg
£ POA
HY-110066R-5MG
25 mg
£ POA
HY-110066R-25MG
10 mg
£ POA
HY-110066R-10MG
100 mg
£ POA
HY-110066R-100MG
50 mg
£ POA
HY-110066R-50MG
About this Product
- SKU:
- HY-110066R
- CAS Number:
- 39025-23-5
- Extra Details:
- (Z)-Guggulsterone (Standard) is the analytical standard of (Z)-Guggulsterone. This product is intended for research and analytical applications. (Z)-Guggulsterone; a constituent of Indian Ayurvedic medicinal plant Commiphora mukul; inhibits the growth of human prostate cancer cells by causing apoptosis. (Z)-Guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis[1]. (Z)-Guggulsterone is also a potent FXR antagonist. (Z)-Guggulsterone reduces ACE2 expression and SARS-CoV-2 infection[2].
- Molecular Weight:
- 312.45
- References:
- [1]Xiao D, et al. z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo. Mol Cancer Ther. 2008 Jan;7(1):171-80.|[2]Brevini T, et al. FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2. Nature. 2022 Dec 5.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;Apoptosis;Metabolic Enzyme/Protease;PI3K/Akt/mTOR;Protein Tyrosine Kinase/RTK
