(Z)-Guggulsterone
Product Sizes
100 mg
£ POA
HY-110066-100MG
50 mg
£ POA
HY-110066-50MG
5 mg
£ POA
HY-110066-5MG
25 mg
£ POA
HY-110066-25MG
10 mg
£ POA
HY-110066-10MG
10mM/1mL
£ POA
HY-110066-10MM
About this Product
- SKU:
- HY-110066
- CAS Number:
- 39025-23-5
- Extra Details:
- (Z)-Guggulsterone; a constituent of Indian Ayurvedic medicinal plant Commiphora mukul; inhibits the growth of human prostate cancer cells by causing apoptosis. (Z)-Guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis[1]. (Z)-Guggulsterone is also a potent FXR antagonist. (Z)-Guggulsterone reduces ACE2 expression and SARS-CoV-2 infection[2].
- Molecular Weight:
- 312.45
- Purity:
- 99.41
- References:
- [1]Xiao D, et al. z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo. Mol Cancer Ther. 2008 Jan;7(1):171-80.|[2]Brevini T, et al. FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2. Nature. 2022 Dec 5.
- Research Area:
- Cancer; Cardiovascular Disease
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Anti-infection;Apoptosis;Metabolic Enzyme/Protease;PI3K/Akt/mTOR;Protein Tyrosine Kinase/RTK
