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Molecular Biology

Fomivirsen (sodium)

Product Sizes
5 mg
£ POA
HY-109528-5MG
1 mg
£ POA
HY-109528-1MG
10 mg
£ POA
HY-109528-10MG
100 mg
£ POA
HY-109528-100MG
25 mg
£ POA
HY-109528-25MG
50 mg
£ POA
HY-109528-50MG
About this Product
SKU:
HY-109528
Additional Names:
ISIS-2922 sodium
CAS Number:
160369-77-7
Extra Details:
Fomivirsen (ISIS-2922) sodium is an antisense 21 mer phosphorothioate oligonucleotide. Fomivirsen sodium is an antiviral agent that is used cytomegalovirus retinitis (CMV) research; incluiding in AIDs. Fomivirsen sodium binds to and degrades the mRNAs encoding CMV immediate-early 2 protein; thus inhibiting virus proliferation[1][2].
Molecular Weight:
6682.4 (free acid)
Purity:
99.71
References:
[1]M D de Smet, et al. Fomivirsen- a phosphorothioate oligonucleotide for the treatment of CMV retinitis. Ocul Immunol Inflamm. 1999 Dec;7(3-4):189-98.|[2]Anna Kilanowska, et al. In vivo and in vitro studies of antisense oligonucleotides – a review. (Review Article) RSC Adv., 2020, 10, 34501-34516
Research Area:
Infection
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C (Powder; stored under nitrogen)
Type:
Molecular Biology Reagents: Nucleic Acids
Pathway:
Anti-infection
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