Upacicalcet (sodium)
Product Sizes
50 mg
£ POA
HY-109106A-50MG
100 mg
£ POA
HY-109106A-100MG
10 mg
£ POA
HY-109106A-10MG
25 mg
£ POA
HY-109106A-25MG
5 mg
£ POA
HY-109106A-5MG
10mM/1mL
£ POA
HY-109106A-10MM
About this Product
- SKU:
- HY-109106A
- Additional Names:
- SK-1403; AJT240; PLS240
- Application:
- Electron Microscopy
- CAS Number:
- 2052969-18-1
- Extra Details:
- Upacicalcet sodium is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet sodium reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels; reducing hypocalcemia and gastrointestinal complications. Upacicalcet sodium sodium improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet sodium sodium inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet sodium is useful for studying SHPT[1][2].
- Molecular Weight:
- 373.75
- Purity:
- 99.91
- References:
- [1]Hoy SM. Upacicalcet: First Approval. Drugs. 2021;81(13):1593-1596.
- Research Area:
- Endocrinology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C (Powder; sealed storage; away from moisture)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- GPCR/G Protein
