Dornase alfa
Product Sizes
500 μg
HY-108858-500UG
About this Product
- SKU:
- HY-108858
- Additional Names:
- rhDNase
- CAS Number:
- 143831-71-4
- Extra Details:
- Dornase alfa (rhDNase) is a recombinant human deoxyribonuclease I (rhDNase) that can specifically degrade extracellular DNA. Dornase alfa catalyzes the cleavage of DNA released by neutrophils in respiratory mucus; reduces sputum viscosity; thereby improving mucus clearance efficiency; reducing airway obstruction and alleviating inflammatory responses. Dornase alfa can be used to improve lung function (such as FEV_1) in cystic fibrosis (CF); reduce the risk of acute pulmonary exacerbations; and has good in vivo tolerability. Dornase alfa acts locally on the respiratory tract through aerosol inhalation; specifically improving the high viscosity of mucus caused by DNA accumulation and related respiratory symptoms[1][2][3][4].
- Purity:
- 0
- Research Area:
- Inflammation/Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 4[o]C for 2 years; do not freeze
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
