(Rac)-PT2399
Product Sizes
100 mg
£ POA
HY-108697A-100MG
50 mg
£ POA
HY-108697A-50MG
5 mg
£ POA
HY-108697A-5MG
10 mg
£ POA
HY-108697A-10MG
10mM/1mL
£ POA
HY-108697A-10MM
About this Product
- SKU:
- HY-108697A
- CAS Number:
- 1672662-07-5
- Extra Details:
- (Rac)-PT2399 (Compound 10e); the racemate of PT2399; acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM[1].
- Molecular Weight:
- 419.32
- Purity:
- 99.84
- References:
- [1]Wehn PM, et al. Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate (S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1 H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385). J Med Chem. 2018 Nov 8;61(21):9691-9721.
- Research Area:
- Cancer
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C; 3 years; 4[o]C; 2 years (Powder)
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Pathway:
- Metabolic Enzyme/Protease
